Drug Response Implementation Notes
Sample Request Body
{ "gender": "female", "ethnicity": "CHB", "genotypes": { "rs2282679": "AA", "rs1229984": "GG", "rs324650": "TT" } }
Sample Response Body
{ "effectsFound": { "benazepril": { "displayName": "Benazepril", "effects": [ { "genotypeEffect": "Average", "attribute": "Drug effect in lowering blood pressure", "snpCount": "2", "snpList": [ "rs7079", "rs2229437" ] }, { "genotypeEffect": "Average", "attribute": "Drug effect in lowering diastolic blood pressure", "snpCount": "1", "snpList": [ "rs1801133" ] } ], "effectsFoundInEthnicity": "CHB" }, "metformin": { "displayName": "Metformin", "effects": [ { "genotypeEffect": "Average", "attribute": "Drug effect on glycemic response", "snpCount": "1", "snpList": [ "rs11212617" ] } ], "effectsFoundInEthnicity": "CEU" } } }
List of drug keys
Key | Drug |
---|---|
abacavir | Abacavir |
allopurinol | Allopurinol |
aspirin | Aspirin |
atorvastatin | Atorvastatin |
benazepril | Benazepril |
bupropion | Bupropion |
carbamazepine | Carbamazepine |
citalopram | Citalopram |
clopidogrel | Clopidogrel |
diltiazem | Diltiazem |
escitalopram | Escitalopram |
hydrochlorothiazide | Hydrochlorothiazide |
lansoprazole | Lansoprazole |
metformin | Metformin |
metoprolol | Metoprolol |
nicotinePatch | Nicotine Transdermal Patch |
nsaids | Nonsteroidal Anti-Inflammatory Drugs |
omeprazole | Omeprazole |
penicillins | Penicillins (beta-lactam family) |
perindopril | Perindopril |
pravastatin | Pravastatin |
simvastatin | Simvastatin |
thiopurines | Thiopurines (i.e. azathioprine) |
warfarin | Warfarin |